1. Funding period


1.     Bischof LF, Friedrich C, Harms A, S Oslashgaard-Andersen L, van der Does, Chris. 2016. The Type IV Pilus Assembly ATPase PilB of Myxococcus xanthus interacts with the Inner Membrane Platform Protein PilC and the Nucleotide Binding Protein PilM. J Biol Chem. doi:10.1074/jbc.M115.701284.

2.     Blauenburg B, Mielcarek A, Altegoer F, Fage CD, Linne U, Bange G, Marahiel MA. 2016. Crystal Structure of Bacillus subtilis Cysteine Desulfurase SufS and Its Dynamic Interaction with Frataxin and Scaffold Protein SufU. PLoS ONE 11(7):e0158749. doi:10.1371/journal.pone.0158749.

3.     Chang Y, Rettberg LA, Treuner-Lange A, Iwasa J, Søgaard-Andersen L, Jensen GJ. 2016. Architecture of the type IVa pilus machine. Science 351(6278):aad2001. doi:10.1126/science.aad2001.

4.     Medeot DB, Rivero MR, Cendoya E, Contreras-Moreira B, Rossi FA, Fischer SE, Becker A, Jofré E. 2016. Sinorhizobium meliloti low molecular weight phosphotyrosine phosphatase SMc02309 modifies activity of the UDP-glucose pyrophosphorylase ExoN involved in succinoglycan biosynthesis. Microbiology (Reading, Engl ). doi:10.1099/mic.0.000239.

5.     Medeot DB, Rivero MR, Cendoya E, Contreras-Moreira B, Rossi FA, Fischer SE, Becker A, Jofré E. 2016. Sinorhizobium meliloti low molecular weight phosphotyrosine phosphatase SMc02309 modifies activity of the UDP-glucose pyrophosphorylase ExoN involved in succinoglycan biosynthesis. Microbiology (Microbiology Society Journal.

6.     Widderich N, Kobus S, Höppner A, Riclea R, Seubert A, Dickschat JS, Heider J, Smits, Sander H J, Bremer E. 2016. Biochemistry and Crystal Structure of Ectoine Synthase: A Metal-Containing Member of the Cupin Superfamily. PLoS ONE 11(3):e0151285. doi:10.1371/journal.pone.0151285.

7.     Skotnicka D, Smaldone GT, Petters T, Trampari E, Liang J, Kaever V, Malone JG, Singer M, Søgaard-Andersen L. 2016 A minimal threshold of c-di-GMP is essential for fruiting body formation and sporulation in Myxococcus xanthus. PLOS Genetics. 12, e1006080.

8.     Muhr E, Leicht O, Gonzalez Sierra S, Thanbichler M, Heider J. 2015 A Fluorescent Bioreporter for Acetophenone and 1-Phenylethanol derived from a Specifically Induced Catabolic Operon. Front Microbiol. 6:1561. doi: 10.3389/fmicb.2015.01561.



1.     Bauer E, Lampert N, Mikaelyan A, Köhler T, Maekawa K, Brune A. 2015. Physicochemical conditions, metabolites and community structure of the bacterial microbiota in the gut of wood-feeding cockroaches (Blaberidae: Panesthiinae). FEMS Microbiol Ecol 91(2):1–14. doi:10.1093/femsec/fiu028.

2.     Breidenbach B, Blaser MB, Klose M, Conrad R. 2015. Crop rotation of flooded rice with upland maize impacts the resident and active methanogenic microbial community. Environ Microbiol. doi:10.1111/1462-2920.13041.

3.     Brune A, Dietrich C. 2015. The Gut Microbiota of Termites: Digesting the Diversity in the Light of Ecology and Evolution. Annu Rev Microbiol 69:145–166. doi:10.1146/annurev-micro-092412-155715.

4.     Brych A., Mascarenhas J., Jaeger E., Charkiewicz E., Pokorny R., Bölker M., Doehlemann G., Batschauer A. (2015) White collar-1-induced photolyase expression contributes to UV-tolerance of Ustilago maydis. MicrobiologyOpen, doi: 10.1002/mbo3.322.

5.     Castrillo M, Bernhardt A, Ávalos J, Batschauer A, Pokorny R. 2015. Biochemical Characterization of the DASH-Type Cryptochrome CryD From Fusarium fujikuroi. Photochem Photobiol 91(6):1356–1367. doi:10.1111/php.12501.

6.     Geiser E, Przybilla SK, Friedrich A, Buckel W, Blank LM, Bölker M. 2015. Ustilago maydis produces itaconic acid via the unusual intermediate trans-aconitate. Microb Biotechnol(in press).

7.     Giessen TW, Altegoer F, Nebel AJ, Steinbach RM, Bange G, Marahiel MA. 2015. A synthetic adenylation-domain-based tRNA-aminoacylation catalyst. Angew Chem Int Ed Engl 54(8):2492–2496. doi:10.1002/anie.201410047.

8.     Jung A, Eisheuer S, Cserti E, Leicht O, Strobel W, Möll A, Schlimpert S, Kühn J, Thanbichler M. 2015. Molecular toolbox for genetic manipulation of the stalked budding bacterium Hyphomonas neptunium. Appl Environ Microbiol 81(2):736–744. doi:10.1128/AEM.03104-14.

9.     Kim Y, Liesack W. 2015. Differential assemblage of functional units in paddy soil microbiomes. PLoS ONE 10(4):e0122221. doi:10.1371/journal.pone.0122221.

10.   Kobus S, Widderich N, Hoeppner A, Bremer E, Smits, Sander H J. 2015. Overproduction, crystallization and X-ray diffraction data analysis of ectoine synthase from the cold-adapted marine bacterium Sphingopyxis alaskensis. Acta Crystallogr F Struct Biol Commun 71(Pt 8):1027–1032. doi:10.1107/S2053230X15011115.

11.   Lang K, Schuldes J, Klingl A, Poehlein A, Daniel R, Brunea A. 2015. New mode of energy metabolism in the seventh order of methanogens as revealed by comparative genome analysis of “Candidatus methanoplasma termitum”. Appl Environ Microbiol 81(4):1338–1352. doi:10.1128/AEM.03389-14.

12.   Lang, K., Schuldes, J., Klingl, A.s, Poehlein, A., Daniel, R., Brune, A. 2015. Comparative Genome Analysis of "Candidatus Methanoplasma termitum" Indicates a New Mode of Energy Metabolism in the Seventh Order of Methanogens. Appl Environ Microbiol(81-4):1338–1352.

13.   Li H, Dietrich C, Zhu N, Mikaelyan A, Ma B, Pi R, Liu Y, Yang M, Brune A, Mo J. 2015. Age polyethism drives community structure of the bacterial gut microbiota in the fungus-cultivating termite Odontotermes formosanus. Environ Microbiol. doi:10.1111/1462-2920.13046.

14.   Meyer BH, Birich A, Albers S. 2015. N-Glycosylation of the archaellum filament is not important for archaella assembly and motility, although N-Glycosylation is essential for motility in Sulfolobus acidocaldarius. Biochimie 118:294–301. doi:10.1016/j.biochi.2014.10.018.

15.   Mielcarek A, Blauenburg B, Miethke M, Marahiel MA. 2015. Molecular insights into frataxin-mediated iron supply for heme biosynthesis in Bacillus subtilis. PLoS ONE 10(3):e0122538. doi:10.1371/journal.pone.0122538.

16.   Mikaelyan A, Dietrich C, Köhler T, Poulsen M, Sillam-Dussès D, Brune A. 2015. Diet is the primary determinant of bacterial community structure in the guts of higher termites. Mol Ecol 24(20):5284–5295. doi:10.1111/mec.13376.

17.   Mikaelyan A, Köhler T, Lampert N, Rohland J, Boga H, Meuser K, Brune A. 2015. Classifying the bacterial gut microbiota of termites and cockroaches: A curated phylogenetic reference database (DictDb). Syst Appl Microbiol 38(7):472–482. doi:10.1016/j.syapm.2015.07.004.

18.   Muhr E, Schühle K, Clermont L, Sünwoldt K, Kleinsorge D, Seyhan D, Kahnt J, Schall I, Cordero PR, Schmitt G, Heider J. 2015. Enzymes of anaerobic ethylbenzene and p-ethylphenol catabolism in 'Aromatoleum aromaticum': differentiation and differential induction. Arch Microbiol 197(9):1051–1062. doi:10.1007/s00203-015-1142-z.

19.   Rietzschel N, Pierik AJ, Bill E, Lill R, Mühlenhoff U. 2015. The basic leucine zipper stress response regulator Yap5 senses high-iron conditions by coordination of [2Fe-2S] clusters. Mol Cell Biol 35(2):370–378. doi:10.1128/MCB.01033-14.

20.   Rossmassler K, Dietrich C, Thompson C, Mikaelyan A, Nonoh JO, Scheffrahn RH, Sillam-Dussès D, Brune A. 2015. Metagenomic analysis of the microbiota in the highly compartmented hindguts of six wood- or soil-feeding higher termites. Microbiome 3:56. doi:10.1186/s40168-015-0118-1.

21.   Schäper S, Krol E, Skotnicka D, Kaever V, Hilker R, Søgaard-Andersen L, Becker A. 2015. Cyclic di-GMP regulates multiple cellular functions in the symbiotic α-proteobacterium Sinorhizobium meliloti. J Bacteriol(in press). doi:10.1128/JB.00795-15.

22.   Skotnicka D, Petters T, Heering J, Hoppert M, Kaever V, Søgaard-Andersen L. 2015. c-di-GMP regulates type IV pili-dependent-motility in Myxococcus xanthus. J Bacteriol(in press). doi:10.1128/JB.00281-15.

23.   Tagua VG, Pausch M, Eckel M, Gutiérrez G, Miralles-Durán A, Sanz C, Eslava AP, Pokorny R, Corrochano LM, Batschauer A. 2015. Fungal cryptochrome with DNA repair activity reveals an early stage in cryptochrome evolution. Proc Natl Acad Sci U S A. doi:10.1073/pnas.1514637112.

24.   Wegner C, Liesack W. 2015. Microbial community dynamics during the early stages of plant polymer breakdown in paddy soil. Environ Microbiol. doi:10.1111/1462-2920.12815.



1.     Bang C, Ehlers C, Orell A, Prasse D, Spinner M, Gorb SN, Albers S, Schmitz RA. 2014. Biofilm formation of mucosa-associated methanoarchaeal strains. Front Microbiol 5:353. doi:10.3389/fmicb.2014.00353.

2.     Brandt FB, Breidenbach B, Brenzinger K, Conrad R. 2014. Impact of short-term storage temperature on determination of microbial community composition and abundance in aerated forest soil and anoxic pond sediment samples. Syst Appl Microbiol 37(8):570–577. doi:10.1016/j.syapm.2014.10.007.

3.     Breidenbach B, Conrad R. 2014. Seasonal dynamics of bacterial and archaeal methanogenic communities in flooded rice fields and effect of drainage. Front Microbiol 5:752. doi:10.3389/fmicb.2014.00752.

4.     Bremer E. 2014. Liberate and grab it, ingest and digest it: the GbdR regulon of the pathogen Pseudomonas aeruginosa. J Bacteriol 196(1):3–6. doi:10.1128/JB.01243-13.

5.     Brune A. 2014. Symbiotic digestion of lignocellulose in termite guts. Nat Rev Microbiol 12(3):168–180. doi:10.1038/nrmicro3182.

6.     Conrad R, Ji Y, Noll M, Klose M, Claus P, Enrich-Prast A. 2014. Response of the methanogenic microbial communities in Amazonian oxbow lake sediments to desiccation stress. Environ Microbiol 16(6):1682–1694. doi:10.1111/1462-2920.12267.

7.     Dietrich C, Brune A. 2014. The complete mitogenomes of six higher termite species reconstructed from metagenomic datasets (Cornitermes sp., Cubitermes ugandensis, Microcerotermes parvus, Nasutitermes corniger, Neocapritermes taracua, and Termes hospes). Mitochondrial DNA:1–2. doi:10.3109/19401736.2014.987257.

8.     Dietrich C, Köhler T, Brune A. 2014. The cockroach origin of the termite gut microbiota: patterns in bacterial community structure reflect major evolutionary events. Appl Environ Microbiol 80(7):2261–2269. doi:10.1128/AEM.04206-13.

9.     Freitag J, Ast J, Linne U, Stehlik T, Martorana D, Bölker M, Sandrock B. 2014. Peroxisomes contribute to biosynthesis of extracellular glycolipids in fungi. Mol Microbiol 93(1):24–36. doi:10.1111/mmi.12642.

10.   Friedrich C, Bulyha I, Søgaard-Andersen L. 2014. Outside-in assembly pathway of the type IV pilus system in Myxococcus xanthus. J Bacteriol 196(2):378–390. doi:10.1128/JB.01094-13.

11.   Gsaller F, Hortschansky P, Beattie SR, Klammer V, Tuppatsch K, Lechner BE, Rietzschel N, Werner ER, Vogan AA, Chung D, Mühlenhoff U, Kato M, Cramer RA, Brakhage AA, Haas H. 2014. The Janus transcription factor HapX controls fungal adaptation to both iron starvation and iron excess. EMBO J 33(19):2261–2276. doi:10.15252/embj.201489468.

12.   Henche A, van Wolferen M, Ghosh A, Albers S. 2014. Dissection of key determinants of cleavage activity in signal peptidase III (SPaseIII) PibD. Extremophiles 18(5):905–913. doi:10.1007/s00792-014-0675-4.

13.   Hoeppner A, Widderich N, Bremer E, Smits, Sander H J. 2014. Overexpression, crystallization and preliminary X-ray crystallographic analysis of the ectoine hydroxylase from Sphingopyxis alaskensis. Acta Crystallogr F Struct Biol Commun 70(Pt 4):493–496. doi:10.1107/S2053230X14004798.

14.   Höppner A, Widderich N, Lenders M, Bremer E, Smits, Sander H J. 2014. Crystal structure of the ectoine hydroxylase, a snapshot of the active site. J Biol Chem 289(43):29570–29583. doi:10.1074/jbc.M114.576769.

15.   Keilberg D, Søgaard-Andersen L. 2014. Regulation of bacterial cell polarity by small GTPases. Biochemistry 53(12):1899–1907. doi:10.1021/bi500141f.

16.   Kim Y, Liesack W. 2014. DAFGA: diversity analysis of functional gene amplicons. Bioinformatics 30(19):2820–2821. doi:10.1093/bioinformatics/btu394.

17.   Kim Yongkyu, Wegner Carl-Eric, Liesack Werner. 2014. Soil Metatranscriptomics. Omics in Soil Science, Caister Academic Press: Caister Academic Press:63–93.

18.   Konovalova A, Søgaard-Andersen L, Kroos L. 2014. Regulated proteolysis in bacterial development. FEMS Microbiol Rev 38(3):493–522. doi:10.1111/1574-6976.12050.

19.   Krol E, Becker A. 2014. Rhizobial homologs of the fatty acid transporter FadL facilitate perception of long-chain acyl-homoserine lactone signals. Proc Natl Acad Sci U S A 111(29):10702–10707. doi:10.1073/pnas.1404929111.

20.   Lanver D, Berndt P, Tollot M, Naik V, Vranes M, Warmann T, Münch K, Rössel N, Kahmann R. 2014. Plant surface cues prime Ustilago maydis for biotrophic development. PLoS Pathog 10(7):e1004272. doi:10.1371/journal.ppat.1004272.

21.   Lill R, Srinivasan V, Mühlenhoff U. 2014. The role of mitochondria in cytosolic-nuclear iron–sulfur protein biogenesis and in cellular iron regulation. Curr Opin Microbiol 22:111–119. doi:10.1016/j.mib.2014.09.015.

22.   Mikaelyan, A., Strassert, J.F.H., Tokuda, G., Brune, A. 2014. The fiber-associated cellulolytic bacterial community in the hindgut of wood-feeding higher termites. Environ. Microbiol.(16):2711–2722.

23.   Netz, Daili J A, Mascarenhas J, Stehling O, Pierik AJ, Lill R. 2014. Maturation of cytosolic and nuclear iron-sulfur proteins. Trends Cell Biol 24(5):303–312. doi:10.1016/j.tcb.2013.11.005.

24.   Siewering K, Jain S, Friedrich C, Webber-Birungi MT, Semchonok DA, Binzen I, Wagner A, Huntley S, Kahnt J, Klingl A, Boekema EJ, Søgaard-Andersen L, van der Does, Chris. 2014. Peptidoglycan-binding protein TsaP functions in surface assembly of type IV pili. Proc Natl Acad Sci U S A 111(10):E953-61. doi:10.1073/pnas.1322889111.

25.   Srinivasan V, Pierik AJ, Lill R. 2014. Crystal structures of nucleotide-free and glutathione-bound mitochondrial ABC transporter Atm1. Science 343(6175):1137–1140. doi:10.1126/science.1246729.

26.   Treuner-Lange A, Søgaard-Andersen L. 2014. Regulation of cell polarity in bacteria. J Cell Biol 206(1):7–17. doi:10.1083/jcb.201403136.

27.   Webert H, Freibert S, Gallo A, Heidenreich T, Linne U, Amlacher S, Hurt E, Mühlenhoff U, Banci L, Lill R. 2014. Functional reconstitution of mitochondrial Fe/S cluster synthesis on Isu1 reveals the involvement of ferredoxin. Nat Commun 5:5013. doi:10.1038/ncomms6013.

28.   Widderich N, Höppner A, Pittelkow M, Heider J, Smits, Sander H J, Bremer E. 2014. Biochemical properties of ectoine hydroxylases from extremophiles and their wider taxonomic distribution among microorganisms. PLoS ONE 9(4):e93809. doi:10.1371/journal.pone.0093809.

29.   Widderich N, Pittelkow M, Höppner A, Mulnaes D, Buckel W, Gohlke H, Smits, Sander H J, Bremer E. 2014. Molecular dynamics simulations and structure-guided mutagenesis provide insight into the architecture of the catalytic core of the ectoine hydroxylase. J Mol Biol 426(3):586–600. doi:10.1016/j.jmb.2013.10.028.



1.     Angel R, Conrad R. 2013. Elucidating the microbial resuscitation cascade in biological soil crusts following a simulated rain event. Environ Microbiol 15(10):2799–2815. doi:10.1111/1462-2920.12140.

2.     Aschenbach K, Conrad R, Reháková K, Doležal J, Janatková K, Angel R. 2013. Methanogens at the top of the world: occurrence and potential activity of methanogens in newly deglaciated soils in high-altitude cold deserts in the Western Himalayas. Front Microbiol 4:359. doi:10.3389/fmicb.2013.00359.

3.     Becker J, Schäfer R, Kohlstedt M, Harder BJ, Borchert NS, Stöveken N, Bremer E, Wittmann C. 2013. Systems metabolic engineering of Corynebacterium glutamicum for production of the chemical chaperone ectoine. Microb Cell Fact 12:110. doi:10.1186/1475-2859-12-110.

4.     Bosello M, Zeyadi M, Kraas FI, Linne U, Xie X, Marahiel MA. 2013. Structural characterization of the heterobactin siderophores from Rhodococcus erythropolis PR4 and elucidation of their biosynthetic machinery. J Nat Prod 76(12):2282–2290. doi:10.1021/np4006579.

5.     Froschauer EM, Rietzschel N, Hassler MR, Binder M, Schweyen RJ, Lill R, Mühlenhoff U, Wiesenberger G. 2013. The mitochondrial carrier Rim2 co-imports pyrimidine nucleotides and iron. Biochem J 455(1):57–65. doi:10.1042/BJ20130144.

6.     Haunhorst P, Hanschmann E, Bräutigam L, Stehling O, Hoffmann B, Mühlenhoff U, Lill R, Berndt C, Lillig CH. 2013. Crucial function of vertebrate glutaredoxin 3 (PICOT) in iron homeostasis and hemoglobin maturation. Mol Biol Cell 24(12):1895–1903. doi:10.1091/mbc.E12-09-0648.

7.     Meyer BH, Albers S. 2013. Hot and sweet: protein glycosylation in Crenarchaeota. Biochem Soc Trans 41(1):384–392. doi:10.1042/BST20120296.

8.     Meyer BH, Peyfoon E, Dietrich C, Hitchen P, Panico M, Morris HR, Dell A, Albers S. 2013. Agl16, a thermophilic glycosyltransferase mediating the last step of N-Glycan biosynthesis in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius. J Bacteriol 195(10):2177–2186. doi:10.1128/JB.00035-13.

9.     Miethke M, Kraushaar T, Marahiel MA. 2013. Uptake of xenosiderophores in Bacillus subtilis occurs with high affinity and enhances the folding stabilities of substrate binding proteins. FEBS Lett 587(2):206–213. doi:10.1016/j.febslet.2012.11.027.

10.   Miethke M, Monteferrante CG, Marahiel MA, van Dijl, Jan Maarten. 2013. The Bacillus subtilis EfeUOB transporter is essential for high-affinity acquisition of ferrous and ferric iron. Biochim Biophys Acta 1833(10):2267–2278. doi:10.1016/j.bbamcr.2013.05.027.

11.   Orell A, Peeters E, Vassen V, Jachlewski S, Schalles S, Siebers B, Albers S. 2013. Lrs14 transcriptional regulators influence biofilm formation and cell motility of Crenarchaea. ISME J 7(10):1886–1898. doi:10.1038/ismej.2013.68.

12.   Scavino AF, Ji Y, Pump J, Klose M, Claus P, Conrad R. 2013. Structure and function of the methanogenic microbial communities in Uruguayan soils shifted between pasture and irrigated rice fields. Environ Microbiol 15(9):2588–2602. doi:10.1111/1462-2920.12161.

13.   Schladebeck S, Mösch H. 2013. The RNA-binding protein Whi3 is a key regulator of developmental signaling and ploidy in Saccharomyces cerevisiae. Genetics 195(1):73–86. doi:10.1534/genetics.113.153775.

14.   Stehling O, Lill R. 2013. The role of mitochondria in cellular iron-sulfur protein biogenesis: mechanisms, connected processes, and diseases. Cold Spring Harb Perspect Biol 5(8):a011312. doi:10.1101/cshperspect.a011312.

15.   Uzarska MA, Dutkiewicz R, Freibert S, Lill R, Mühlenhoff U. 2013. The mitochondrial Hsp70 chaperone Ssq1 facilitates Fe/S cluster transfer from Isu1 to Grx5 by complex formation. Mol Biol Cell 24(12):1830–1841. doi:10.1091/mbc.E12-09-0644.



1.     Ma K, Conrad R, Lu Y. 2012. Responses of methanogen mcrA genes and their transcripts to an alternate dry/wet cycle of paddy field soil. Appl Environ Microbiol 78(2):445–454. doi:10.1128/AEM.06934-11.

2.     Paul K, Nonoh JO, Mikulski L, Brune A. 2012. "Methanoplasmatales," Thermoplasmatales-related archaea in termite guts and other environments, are the seventh order of methanogens. Appl Environ Microbiol 78(23):8245–8253. doi:10.1128/AEM.02193-12.