2. Funding Period

D 1   Hannes Link

Donati S, Sander T, Link H. 2018.

Crosstalk between transcription and metabolism: how much enzyme is enough for a cell? WIREs Systems Biology and Medicine 10: e1396.

Guder JC, Schramm T, Sander T, Link H. 2017.

Time-optimized isotope ratio LC-MS/MS for high-throughput guantification of primary metabolites. Analytical Chemistry 89: 1624-1631.

Han D, Link H, Liesack W. 2017.

Response of Methylocystis sp. strain SC2 to salt Stress: physiology, global transcriptome, and amino acid profiles. Applied and Environmental Microbiology 83: e00866-17.        

 
 
D 2   Tobias Erb

Bernhardsgrütter I, Vögeli B, Wagner T, Peter DM, Cortina NS, Bange G, Engilberge S, Girard E, Riobé F, Maury O, Shima S, Zarzycki J, Erb TJ. 2018.

The multi-catalytic compartment of propionyl-CoA synthase sequesters a toxic metabolite, Nature Chemical Biology, in press.

Schada von Borzyskowski L, Sonntag F, Pöschel L, Vorholt JA, Schrader J, Erb TJ, Buchhaupt M. 2018.

Replacing the ethylmalonyl-CoA pathway with the glyoxylate shunt provides metabolic flexibility in the central carbon metabolism of Methylobacterium extorquens AM1. ACS Synthetic Biology 7:86-97.

 

 
D 4   Uwe Maier
Stukenberg D, Zauner S, Dell' Aquila G, Maier U.G. 2018. Optimizing CRISPR/Cas9 for the diatom Phaeodactylum tricornutum. Front. Plant Sci 10.3389/fpls.2018.00740 
 
 
D 5   Roland Lill & Ulrich Mühlenhoff

Uzarska, MA, Przybyla-Toscano J, Spantgar F, Zannini F, Lill R, Mühlenhoff U, Rouhier N. 2018.

Conserved functions of Arabidopsis mitochondrial late-acting maturation factors in the trafficking of iron-sulfur clusters. Biochim. Biophys. Acta 1865, 1250-1259.

Braymer JJ, Lill R. 2017.

Iron-sulfur cluster biogenesis and trafficking in mitochondria. J. Biol Chem 292:12754–12763.

Freibert SA, Goldberg AV, Hacker C, Molik S, Dean P, Williams TA, Nakjang S, Long S, Sendra K, Bill E, Heinz E, Hirt RP, Lucocq JM, Embley TM, Lill R. 2017.

Evolutionary conservation and in vitro reconstitution of microsporidian iron-sulfur cluster biosynthesis. Nat Commun 8:13932.

Li H, Stümpfig M, Zhang C, An X, Stubbe J, Lill R, Huang M. 2017.

The diferric-tyrosyl radical cluster of ribonucleotide reductase and cytosolic iron-sulfur clusters have distinct and similar biogenesis requirements. J Biol Chem 292:11445-11451.

Garcia-Santamarina S, Uzarska MA, Festa RA, Lill R, Thiele DJ. 2017.

Cryptococcus neoformans iron-sulfur protein biogenesis machinery is a novel layer of protection against Cu stress. mBio 8:e01742-17. 

Legati A, Reyes A, Ceccatelli Berti C, Stehling O, Marchet S, Lamperti C, Ferrari A, Robinson AJ, Mühlenhoff U, Lill R, Zeviani M, Goffrini P, Ghezzi D. 2017.

A novel de novo dominant mutation in ISCU associated with mitochondrial myopathy. J Med Genet 54:815-824.

Christ S. Leichert LI, Willms A, Lill R, Mühlenhoff U. 2016.

Defects in mitochondrial iron-sulfur cluster assembly induce cysteine S-polythiolation on iron-sulfur apoproteins. Antioxid Redox Signal 25: 28–40.

Melber A, Na U, Vashisht A, Weiler BD, Lill R, Wohlschlegel JA, Winge DR 2016.

Role of Nfu1 and Bol3 in iron-sulfur cluster transfer to mitochondrial clients. Elife 5. e15991

Netz Daili JA, Genau HM, Weiler BD, Bill E, Pierik AJ, Lill R. 2016.

The conserved protein Dre2 uses essential [2Fe-2S] and [4Fe-4S] clusters for its function in cytosolic iron-sulfur protein assembly. Biochem J 473: 2073–2085.

Uzarska MA, Nasta V, Weiler BD, Spantgar F, Ciofi-Baffoni S, Saviello MR, Gonnelli L, Mühlenhoff U, Banci L, Lill R. 2016.

Mitochondrial Bol1 and Bol3 function as assembly factors for specific iron-sulfur proteins. eLife 5:e16673.

 
 
D 6   Michael Bölker

Geiser E, Przybilla SK, Friedrich A, Buckel W, Wierckx N, Blank LM, Bölker M. 2016.

Ustilago maydis produces itaconic acid via the unusual intermediate trans-aconitate. Microb Biotechnol 9:116-26.

Brych A, Mascarenhas J, Jaeger E, Charkiewicz E, Pokorny R, Bölker M, Doehlemann G, Batschauer A. 2016

White collar 1-induced photolyase expression contributes to UV-tolerance of Ustilago maydis. Microbiologyopen 5:224-43.

 
 
D 7   Erhard Bremer

Czech L, Hermann L, Stöveken N, Richter A, Hoeppner A, Smits SHJ, Heider J, Bremer E. 2018.

Role of the extremolytes ectoine and hydroxyectoine as stress protectants and nutrients: genetics, phylogenomics, biochemistry, and structural analysis. Genes 9, 177

Czech L, Bremer E. 2018.

With a pinch of extra salt - did predatory protists steal genes from their food? PLoS Biol 16:e2005163

Jose MJ, Hoffmann T, Sanchez-Porro C, Heider J, Ventosa A, Bremer E. 2018.

Compatible solute synthesis and import by the moderate halophile Spiribacter salinus: physiology and genomics. Front Microbiol 9:108

Czech L, Poehl S, Hub P, Stoeveken N, Bremer E. 2018.

Tinkering with osmotically controlled transcription allows enhanced production and excretion of ectoine and hydroxyectoine from a microbial cell factory. Appl Environ Microbiol 84:e01772-17

Schulz A, Hermann L, Freibert S, Bönig T, Hoffmann T, Riclea R, Dickschat J, Heider J, Bremer E. 2017.

Transcriptional regulation of ectoine catabolism in response to multiple metabolic and environmental cues. Env Microbiol 19:4599-4619

Schulz A, Stöveken N, Binzen IM, Hoffmann T, Heider J, Bremer E. 2017

Feeding on compatible solutes: a substrate-induced pathway for uptake and catabolism of ectoines and its genetic control by EnuR. Environ Microbiol 19: 926–946.

Czech L, Stöveken N, Bremer E. 2016

EctD-mediated biotransformation of the chemical chaperone ectoine into hydroxyectoine and its mechanosensitive channel-independent excretion. Microb Cell Fact 15: 126.

Widderich N, Czech L, Elling FJ, Könneke M, Stöveken N, Pittelkow M, et al. 2016

Strangers in the archaeal world: osmostress-responsive biosynthesis of ectoine and hydroxyectoine by the marine thaumarchaeon Nitrosopumilus maritimus. Environ Microbiol 18: 1227–1248.

Widderich N, Kobus S, Höppner A, Riclea R, Seubert A, Dickschat JS, et al. 2016

Biochemistry and crystal structure of ectoine synthase: a metal-containing member of the cupin superfamily. PLoS ONE 11: e0151285.

Widderich N, Bremer E, Smits SHJ. 2016

The Ectoine hydroxylase: a nonheme-containing iron(II) and 2-oxoglutarate-dependent dioxygenase. In Encyclopedia of Inorganic and Bioinorganic Chemistry.

 
 
D 8   Werner Liesack

Han D, Dedysh SN, Liesack W. 2018.

Unusual genomic traits suggest Methylocystis bryophila S285 to be well adapted for life in peatlands. Genome Biol. Evol. 10, 623-628.

Hakobyan A, Liesack W, Glatter T. 2018.

Crude-MS strategy for in-depth proteome analysis of the methane-oxidizing Methylocystis sp. strain SC2. J. Proteome Res. 17, 3086-3103.

Peng J, Wegner C-E, Liesack W. 2017.

Short-term exposure of paddy soil microbial communities to salt stress triggers different transcriptional responses of key taxonomic groups. Front Microbiol 8: 400.

Wegner C-E, Liesack W. 2017.

Unexpected dominance of elusive Acidobacteria in early industrial soft coal slags. Front Microbiol 8: 1023.

Han D, Link H, Liesack W. 2017.

Response of Methylocystis sp. strain SC2 to salt stress: Physiology, global transcriptome, and amino acid profiles. Appl Environ Microbiol 83:e00866-17. 

 
 
D 9   Andreas Brune

Bourguignon T, Lo N, Dietrich C, Šobotník J, Sidek S, Roisin Y, Brune A, Evans TA. 2018.

Rampant host-switching shaped the termite gut microbiome. Curr. Biol. 28: 649-654.e2. 

Tegtmeier D, Belitz A, Radek R, Heimerl T, Brune A. 2018.

Ereboglobus luteus gen. nov. sp. nov. from cockroach guts, and new insights into the oxygen relationship of the genera Opitutus and Didymococcus (Verrucomicrobia: Opitutaceae). Syst. Appl. Microbiol. 41: 101–112.

Mikaelyan A, Thompson CL, Meuser K, Zheng H, Rani P, Plarre R, Brune A. 2017.

High-resolution phylogenetic analysis of Endomicrobia reveals multiple acquisitions of endosymbiotic lineages by termite gut flagellates. Environ. Microbiol. Rep. 9: 477–483.

Zheng H, Dietrich C, Brune A. 2017.

Genome analysis of Endomicrobium proavitum suggests loss and gain of relevant functions during the evolution of intracellular symbionts. Appl. Environ. Microbiol. 83: e00656-17.

Mikaelyan A, Meuser K, Brune A. 2017.

Microenvironmental heterogeneity of gut compartments drives bacterial community structure in wood- and humus-feeding higher termites. FEMS Microbiol Ecol 93: fiw20.

Hervé V, Brune A. 2017

The complete mitochondrial genomes of the higher termites Labiotermes labralis and Embiratermes neotenicus (Termitidae: Syntermitinae). Mitochondr. DNA Part B 2: 109–110.

Li H, Dietrich C, Zhu N, Mikaelyan A, Ma B, Pi R, Liu Y, Yang M, Brune A, Mo J. 2016.

Age polyethism drives community structure of the bacterial gut microbiota in the fungus-cultivating termite Odontotermes formosanus. Environ Microbiol 18:1440–1451.

 
E 1   Alfred Batschauer

Orth C, Niemann N, Hennig L, Essen L-O, Batschauer A. 2017.

Hyperactivity of the Arabidopsis cryptochrome 1 (cry1) L407F mutant is caused by a structural alteration close to the cry1 ATP-binding site. J. Biol. Chem. 4:292(31): 12906-12920

 
 
E 2   Peter Graumann

Lucena D, Mauri M, Schmidt F, Eckhardt B, Graumann PL. 2018.

Microdomain formation is a general property of bacterial membrane proteins and induces heterogeneity of diffusion patterns. BMC Biol. 16(1):97. doi: 10.1186

 
 
E 3   Hans-Ulrich Mösch
 
 
 
E 4   Martin Thanbichler
 
 
 
E 5   Anke Becker

Schäper S, Yau HCL, Krol E, Skotnicka D, Heimerl T, Gray J, Kaever V, Søgaard-Andersen L, Vollmer W, Becker A. 2018

Seven-transmembrane receptor protein RgsP and cell wall-binding protein RgsM promote unipolar growth in Rhizobiales. PLoS Genet 14:e1007594.

Baumgardt K, Melior H, Madhugiri R, Thalmann S, Schikora A, McIntosh M, Becker A, Evguenieva-Hackenberg E. 2017.

RNase E and RNase J are needed for S-adenosylmethionine homeostasis in Sinorhizobium meliloti. Microbiology SGM 2017: 570–583.

Medeot DB, Rivero MR, Cendoya E, Contreras-Moreira B, Rossi FA. Fischer SE, Becker A, Jofré E 2017.

Sinorhizobium meliloti low molecular weight phosphotyrosine phosphatase SMc02309 modifies activity of the UDP-glucose pyrophosphorylase ExoN involved in succinoglycan biosynthesis. Microbiology SGM 2016: 552–563.

Salas MA, Lozano MJ, Lopez JL, Draghi W, Serrania J, Torres Tejerizo GA, Albicoro FJ, Nilsson JF, Pistorio M, del Papa MF, Parisi G, Becker A, Lagares A. 2017.

Specificity traits consistent with legume-rhizobia coevolution displayed by Sinorhizobium meliloti rhizosphere colonization. Environ Microbiol. 19:3423-3438

Lagares A (Jr.), Borella GC, Linne U, Becker A, Valverde C 2017.

Regulation of polyhydroxybutyrate accumulation in Sinorhizobium meliloti by the 1 trans-encoded small RNA MmgR. J Bacteriol. 199: e00776-16.

Robledo M, Peregrina A, Millán V, García-Tomsig NI, Torres-Quesada O, Mateos PF, et al. 2017.

A conserved α-proteobacterial small RNA contributes to osmoadaptation and symbiotic efficiency of rhizobia on legume roots. Environ Microbiol. 19:2661-2680

Saramago M, Peregrina A, Robledo M, Matos RG, Hilker R, Serrania J, Becker A, Arraiano CM, Jiménez-Zurdo JI. 2017.

Sinorhizobium meliloti YbeY is an endoribonuclease with unprecedented catalytic features, acting as silencing enzyme in riboregulation. Nucl Acids Res: 1371–1391.

Schäper S, Steinchen W, Krol E, Altegoer F, Skotnicka D, Søgaard-Andersen L, et al. 2017.

AraC-like transcriptional activator CuxR binds c-di-GMP by a PilZ-like mechanism to regulate extracellular polysaccharide production. Proc Natl Acad Sci U S A 114: E4822-E4831.

Döhlemann J, Brennecke M, Becker A. 2016.

Cloning-free genome engineering in Sinorhizobium meliloti advances applications of Cre/loxP site-specific recombination. J Biotechnol 233:160-170.

Schäper S, Krol E, Skotnicka D, Kaever V, Hilker R, Søgaard-Andersen L, Becker A. 2016.

Cyclic di-GMP regulates multiple cellular functions in the symbiotic α-proteobacterium Sinorhizobium meliloti. J Bacteriol 198:521-535.

 
 
E 6   Gert Bange

Altegoer A, Mukherjee S, Steinchen W, Bedrunka P, Linne U, Kearns DB, Bange G. 2018.

FliS/flagellin/FliW heterotrimer couples type III secretion and flagellin homeostasis. Scientific Reports 8:11552

Steinchen W, Vogt MS, Altegoer F, Giammarinaro PI, Horvatek H, Wolz C, Bange G. 2018.

Structural and mechanistic divergence of the small (p)ppGpp synthetases RelP and RelQ. Scientific Reports 10.1038/s41598-018-20634-4

Schäper S, Steinchen W, Krol E, Altegoer F, Skotnicka D, Søgaard-Andersen L, et al. 2017.

AraC-like transcriptional activator CuxR binds c-di-GMP by a PilZ-like mechanism to regulate extracellular polysaccharide production. Proc Natl Acad Sci U S A 114: E4822-E4831.

Altegoer F, Rensing SA, Bange G. 2016.

Structural basis for the CsrA-dependent modulation of translation initiation by an ancient regulatory protein. Proc Natl Acad Sci U S A 113: 10168–10173.

Steinchen W, Bange G. 2016.

The magic dance of the alarmones (p)ppGpp. Mol Microbiol 101: 531–544.

 
 
E 7   Knut Drescher

Vidakovic L, Singh PK, Hartmann R, Nadell CD, Drescher K. 2017.

Dynamic biofilm architecture confers individual and collective mechanisms of viral protection. Nat Microbiol 3:26-31.

Singh PK, Bartalomej S, Hartmann R, Jeckel H, Vidakovic L, Nadell CD, Drescher K. 2017.

Vibrio cholerae combines individual and collective sensing to trigger biofilm dispersal. Curr Biol 27:1-8.

Nadell CD, Ricaurte D, Yan J, Drescher K, Bassler BL. 2017.

Flow environment and matrix structure interact to determine spatial competition in Pseudomonas aeruginosa biofilms. eLife 6:e21855.

 
 
E 8   Lotte Søgaard-Andersen

Schäper S, Yau H, Krol E, Skotnicka D, Heimerl T, Gray J, Kaever V, Søgaard-Andersen L, Vollmer W, Becker A. 2018.

Seven-transmembrane receptor protein RgsP and cell wall-binding protein RgsM promote unipolar growth in Rhizobiales. PLoS Genet 14:e1007594

Schumacher D, Søgaard-Andersen L. 2017. 

Regulation of cell polarity in motility and cell division in Myxococcus xanthus. Annu. Rev. Microbiol.: 71, 61-78

Skotnicka D, Søgaard-Andersen L. 2017. 

Type IV pili-dependent motility as a tool to determine the activity of c-di-GMP modulating enzymes in Myxococcus xanthus. Meth. Mol. Biol. 1657: 157-165

Treuner-Lange A, Søgaard-Andersen L. 2017. 

Typ-IVa-Pilus-Motilität - Bislang stärkster molekularer Motor zieht Bakterien über Oberflächen. BIOspektrum: 130–134.

Schäper S, Steinchen W, Krol E, Altegoer F, Skotnicka D, Søgaard-Andersen L, et al. 2017.

AraC-like transcriptional activator CuxR binds c-di-GMP by a PilZ-like mechanism to regulate extracellular polysaccharide production. Proc Natl Acad Sci U S A 114: E4822-E4831.

Skotnicka D, Smaldone GT, Petters T, Trampari E, Liang J, Kaever V, Malone JG, Singer M, Søgaard-Andersen L. 2016.

A minimal threshold of c-di-GMP is essential for fruiting body formation and sporulation in Myxococcus xanthus. PLOS Genetics 12:e1006080.

Bischof LF, Friedrich C, Harms A, Søgaard-Andersen L, Chris van der Does C. 2016.

The type IV pilus assembly ATPase PilB of Myxococcus xanthus interacts with the inner membrane platform protein PilC and the nucleotide binding protein PilM. J Biol Chem 291:6946-6957.

Chang Y-W, Rettberg L, Treuner-Lange A, Iwasa J, Søgaard-Andersen L, Jensen GJ. 2016.

Architecture of the type IVa pilus machine. Science 351:aad2001.

Schäper S, Krol E, Skotnicka D, Kaever V, Hilker R, Søgaard-Andersen L, Becker A. 2016.

cyclic di-GMP regulates multiple cellular functions in the symbiotic α-proteobacterium Sinorhizobium meliloti. J Bacteriol 198:521-535.

Skotnicka D, Petters T, Heering J, Hoppert M, Kaever V, Søgaard-Andersen L. 2016.

c-di-GMP regulates type IV pili-dependent-motility in Myxococcus xanthus. J Bacteriol 198:77-90.

 
E 9   Lars-Oliver Essen

Orth C, Niemann N, Hennig L, Essen L-O, Batschauer A. 2017

Hyperactivity of the Arabidopsis cryptochrome 1 (cry1) L407F mutant is caused by a structural alteration close to the cry1 ATP-binding site. J., Biol. Chem. 292:12906-12920